Latest Conference Articles

TCE Therapy Demonstrates Quick Responses for Systemic Lupus Erthematosus in Early Data

Schett discussed findings from 2 early studies of CD19 CAR T-cell therapy.

Qiubai Li, MD, PhD, director, rheumatology, Union Hospital, and Huazhong University of Science and Technology

Elafibranor Improves Predicted Transplant-Free Survival Based on GLOBE, UK-PBC Scores

A-319 has been well-tolerated so far and dose-escalation is ongoing in the phase 1 trial.

Kris Kowdley, MD | Credit: Velocity Clinical Research

Interim Phase 1 Update Shows Favorable Effect of Nex-z for ATTR-CM

Treatment with elafibranor (Iqirvo) improved prognostic GLOBE and UK-PBC scores as early as week 4 in the phase 3 ELATIVE trial.

VANISH2: Catheter Ablation Viable First-Line Option for Ventricular Tachycardia

A single dose of nex-z achieved consistent and rapid reductions in serum TTR levels over 12 months of follow-up in patients with ATTR-CM.

Chari Cohen, DrPH, MPH: Healthcare Providers’ Role in HBV Clinical Trial Diversity

Initial catheter ablation achieved a lower risk of a composite primary endpoint event than anti-arrhythmic drug therapy in patients who survived a heart attack.

Chari Cohen, DrPH, MPH | Credit: LinkedIn

Rapid Initiation of SGLT2 Inhibitors Improves Cost-Effectiveness of Therapy, with Ankeet Bhatt, MD, MBA

Cohen explains patient perspectives about how healthcare providers can help address the lack of diversity in chronic HBV clinical trials.

By Ankeet Bhatt, MD, MBA
Patrick Campbell

Hide Okuno, MS: Tube Weaning Reduces Parental Stress, Findings Guide Future Studies

Ankeet Bhatt, MD, MBA, discusses a study he led from AHA 2024 examining the cost-effectiveness of dapagliflozin based on how soon therapy was initiated following diagnosis or hospitalization.

Vitamin D Deficiency Linked to Worse Autoimmune Hepatitis Outcomes

At NASPGHAN 2024, Okuno shared findings on reduced parental stress after children’s tube weaning, emphasizing the potential for new outpatient weaning protocols.

Mariana Nunes Ferreira, MD | Credit: Mariana Nunes Ferreira on X

Jonathan Stine, MD: Exercise’s Benefit in MASH is Independent of Weight Loss

Patients with autoimmune hepatitis who are deficient in vitamin D had worse outcomes than patients with normal vitamin D levels.

Jonathan Stine, MD | Credit: Penn State Health

Intensive Blood Pressure Regimen Lowers CVD Risk in People with T2D

Stine reviews findings from a posthoc analysis of the NASHFit trial suggesting the impact of exercise on MASH resolution, even without weight loss.

SUMMIT Trial Proves Tirzepatide's Benefit in HFpEF with Obesity

Reducing systolic blood pressure to less than 120 mmHg lowered the risk of major cardiovascular events for most people with diabetes in the BPROAD trial.

Milton Packer, MD | Credit: American Heart Association

By Patrick Campbell

Telehealth Could Address HCV Care Barriers, Expand Treatment for People Who Inject Drugs

Tirzepatide reduced the risk of heart failure hospitalization or cardiovascular death by 38% and improved body weight by up to 21% in the SUMMIT trial.

Zoi Papalamprakopoulou, MD | Credit: Papalamprakopoulou on LinkedIn

John Stone, MD, MPH: Inebilizumab Efficacious for IgG4-Related Disease in MITIGATE Study

Zoi Papalamprakopoulou, MD, explains telehealth’s potential to aid HCV treatment in high-risk populations and how patients perceive this care modality.

Glucocorticosteroid Use for Rheumatoid Arthritis Increases CVD, Infection Mortality Risk Even After Cessation

Stone discussed findings from the first randomized, double-blind, placebo-controlled trial for IgG4-related disease.

Diane Lacaille, MDCM, MHSc, Scientific Director and Senior Scientist at Arthritis Research Canada and Professor, Department of Medicine, University of British Columbia, Vancouver.

Study Highlights Real-World Characteristics of Providers Treating Psoriasis in US

People who used GC for over 2 years and 3 years had elevated risks of CVD and infection-related mortality, respectively, that never returned to pre-GC use levels.

Study Highlights Real-World Characteristics of Providers Treating Psoriasis in the US

By Tim Smith

Wei Zhang, MD, PhD: Optimizing Post-Liver Transplant Care for High-Risk Patients

In this cross-sectional survey analysis, new insights were explored regarding clinical practice patterns and treatment outcomes within dermatology practices in the US.

Idorsia Launches Aprocitentan (TRYVIO) in US For Treatment of Hypertension

Zhang describes how a novel multidisciplinary care clinic has helped reduce relapse after transplant in patients with alcohol-associated liver disease.

IL-18 Levels Associated With Long COVID Risk in People With Rheumatic Diseases

Once-daily aprocitentan is indicated to help lower blood pressure in adult patients with hypertension who are inadequately controlled on other medications.

Jeffrey Sparks, MD, MMSc, Assistant Professor of Medicine and Associate Physician at Brigham and Women's Hospital and Harvard Medical School

VTP-300, Nivolumab Combination Shows Promise for Functional HBV Cure in Phase 2b Trial

IL-18 levels were consistently lower across participants with different SARDs, remission status, and COVID-19 disease characteristics.

Nadege Pelletier, PhD | Credit: Barinthus Bio

Parent Stress Reduces Over Time When Weaning Child Off Tube Feeding with Hide Okuno, MS

New phase 2b data suggest a combination of VTP-300 and low-dose nivolumab can stimulate immune response and induce HBV functional cure.

Seladelpar (Livdelzi) Demonstrates Long-Term Benefit for Primary Biliary Cholangitis

HCPLive spoke with Okuno at NASPGHAN 2024 about a study examining changes in parent stress levels and mental health symptoms after a child completes weaning off tube feeding.

Eric Lawitz, MD | Credit: Texas Liver Institute

New Review Highlights Variability in Clinical Features, Comorbidities of Biliary Atresia

Findings from a 2.5-year interim analysis from the ongoing phase 3 ASSURE study highlight seladelpar’s sustained efficacy and long-term safety for PBC.

Study Finds Benefits and Risks in Cannabis Use for Rheumatoid Arthritis

November 14th 2024

A study presented at NASPGHAN 2024 reveals rising incidence rates and improved survival outcomes of Biliary Atresia in the US.

Karun Shrestha, MD, Internal Medicine Resident at St Barnabas Hospital and Research Fellow, Acute Care Research Consortium, Mayo Clinic

Kara Margolis, MD: Link Between Maternal SSRI Exposure, Increased Constipation Risk in Infants

November 14th 2024

While an effective and promising strategy for chronic pain relief, more research on long-term cannabis usage is needed.

Debra Silberg, MD, PhD, on Celiac Disease: “The Guidelines Are Really Helpful, but They Have to be in the Right Hands”

November 13th 2024

Maternal SSRI use was linked to a higher risk of constipation in infants, while untreated maternal depression was tied to colic. Margolis discussed these findings at NASPGHAN.

Age, Race, Ethnicity Disparities Hinder Celiac Disease Screening, with Debra Silberg, MD, PhD

November 11th 2024

Silberg urges wider physician education on celiac screening, stressing that guidelines must reach primary care to address disparities and misconceptions.