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Spotlight -

This Year In Medicine 2025

Opinion|Videos|April 30, 2025

Effect of Hypercortisolism on Cardiovascular and Diabetes Care

Author(s)Pamela Kushner, MD, FAAFP , John Anderson, MD, John Buse, MD, PhD

Experts discuss how hypercortisolism contributes to treatment-resistant hypertension and other cardiovascular diseases, the impact of treating hypercortisolism on cardiovascular risks, when cardiologists should suspect hypercortisolism as a contributing factor to cardiovascular disease, the role of hypercortisolism in type 2 diabetes, how it complicates the management of type 2 diabetes and impacts long-term glucose control, and when endocrinologists should suspect hypercortisolism in their patients with type 2 diabetes.

Episodes in this series

EP. 1 Practical Strategies for Identifying and Screening for Hypercortisolism

EP. 1 Practical Strategies for Identifying and Screening for Hypercortisolism

EP. 2 Defining Hypercortisolism and Its Impact on Physical and Mental Health

EP. 2 Defining Hypercortisolism and Its Impact on Physical and Mental Health

EP. 3 Advances in the Understanding of Hypercortisolism

EP. 3 Advances in the Understanding of Hypercortisolism

EP. 4 Key Learnings From the CATALYST Study on Hypercortisolism Prevalence

EP. 4 Key Learnings From the CATALYST Study on Hypercortisolism Prevalence

EP. 5 Overcoming Inertia in Hypercortisolism Identification

EP. 5 Overcoming Inertia in Hypercortisolism Identification

EP. 6 Importance of Primary Care in Identification and Screening for Hypercortisolism

EP. 6 Importance of Primary Care in Identification and Screening for Hypercortisolism

EP. 7 Who to Screen for Hypercortisolism

EP. 7 Who to Screen for Hypercortisolism

EP. 8 Dexamethasone Suppression to Identify Hypercortisolism

EP. 8 Dexamethasone Suppression to Identify Hypercortisolism

EP. 9 Effect of Hypercortisolism on Cardiovascular and Diabetes Care

EP. 9 Effect of Hypercortisolism on Cardiovascular and Diabetes Care

EP. 10 Importance of Multispecialty Communication in Hypercortisolism Management and Referrals

EP. 10 Importance of Multispecialty Communication in Hypercortisolism Management and Referrals

EP. 11 Addressing Potential Barriers to Implementing Hypercortisolism Screening in Practice

EP. 11 Addressing Potential Barriers to Implementing Hypercortisolism Screening in Practice

Video content above is prompted by the following:

How does hypercortisolism contribute to treatment-resistant hypertension and other cardiovascular diseases?
We have mentioned that there are cardiovascular risks associated with hypercortisolism. How does treatment of hypercortisolism impact these risks?
Looking specifically from a cardiology perspective, when should a cardiologist suspect hypercortisolism as a contributing factor to cardiovascular disease?
What is the role of hypercortisolism in type 2 diabetes?
How does hypercortisolism complicate the management of type 2 diabetes, and how does it impact long-term glucose control?
Now, let us shift to the endocrinology perspective. When should an endocrinologist suspect hypercortisolism in their patients with type 2 diabetes?

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