Logo Image
Opinion|Videos|April 16, 2025

Key Learnings From the CATALYST Study on Hypercortisolism Prevalence

Experts discuss the challenges of identifying and diagnosing hypercortisolism, the reasons behind its often-delayed diagnosis, the impact of a wide spectrum of clinical signs and symptoms on clinicians’ ability to diagnose the condition, and recent data on the prevalence of hypercortisolism in at-risk populations, including those with difficult-to-control diabetes, hypertension, and cardiovascular disease.

Episodes in this series

Video content above is prompted by the following:

  • What are some of the challenges of identifying and diagnosing hypercortisolism?
  • The diagnosis of hypercortisolism is often delayed by several years. Why do you think that the diagnosis of hypercortisolism is often delayed or missed?
  • Hypercortisolism presents with a wide spectrum of clinical signs and symptoms. How does this affect clinicians’ ability to diagnose this condition?
  • The prevalence of hypercortisolism in certain at-risk patients is higher than previously thought. Can you discuss some of the recent data on hypercortisolism prevalence?
  • Prevalence of hypercortisolism in patients with difficult-to-control diabetes was 24%.
  • Prevalence of hypercortisolism in patients with difficult-to-control diabetes and difficult-to-control hypertension was 40%.
  • Patients with cardiovascular disease had a higher prevalence of hypercortisolism than those without (33.3% vs 20.9%).

Related to this article

View more