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This Year In Medicine 2025

Opinion|Videos|April 11, 2025

Oral JAK Inhibitors’ Place in Atopic Dermatitis Guidelines

Author(s)Linda Stein Gold, MD, Lisa Swanson, MD, PhD, James Song, MD

Experts discuss the current place of JAK inhibitors in atopic dermatitis management, highlighting their role as an effective oral treatment option within the broader spectrum of therapies, including topical treatments and biologics, depending on disease severity and patient needs.

Episodes in this series

EP. 1 The Role of the JAK/STAT Signaling Pathway in Atopic Dermatitis

EP. 1 The Role of the JAK/STAT Signaling Pathway in Atopic Dermatitis

EP. 2 JAK1 Selective Inhibition and the Impact of Selectivity on Efficacy and Safety

EP. 2 JAK1 Selective Inhibition and the Impact of Selectivity on Efficacy and Safety

EP. 3 Long-Term Efficacy and Safety of JAK Inhibitors in Atopic Dermatitis

EP. 3 Long-Term Efficacy and Safety of JAK Inhibitors in Atopic Dermatitis

EP. 4 Understanding the Origins of the Boxed Warning for JAK Inhibitors

EP. 4 Understanding the Origins of the Boxed Warning for JAK Inhibitors

EP. 5 Communicating With Patients on the Safety of JAK Inhibitors in Atopic Dermatitis

EP. 5 Communicating With Patients on the Safety of JAK Inhibitors in Atopic Dermatitis

EP. 6 Laboratory Monitoring Plans for Oral JAK Inhibitors

EP. 6 Laboratory Monitoring Plans for Oral JAK Inhibitors

EP. 7 Oral JAK Inhibitors’ Place in Atopic Dermatitis Guidelines

EP. 7 Oral JAK Inhibitors’ Place in Atopic Dermatitis Guidelines

EP. 8 Utilizing Patient Factors to Guide Treatment Selection in Atopic Dermatitis

EP. 8 Utilizing Patient Factors to Guide Treatment Selection in Atopic Dermatitis

EP. 9 Addressing Treatment Response and Switching Among Systemic Therapies in Atopic Dermatitis

EP. 9 Addressing Treatment Response and Switching Among Systemic Therapies in Atopic Dermatitis

EP. 10 Oral JAK Inhibitor Dose Escalation in Atopic Dermatitis Treatment

EP. 10 Oral JAK Inhibitor Dose Escalation in Atopic Dermatitis Treatment

EP. 11 Key Takeaways on the Role of Oral JAK Inhibitors in Atopic Dermatitis Management

EP. 11 Key Takeaways on the Role of Oral JAK Inhibitors in Atopic Dermatitis Management

Video content above is prompted by the following:

What is the current place in therapy for JAK inhibitors in atopic dermatitis management, particularly when considering the spectrum of treatment options, including topical therapies and biologics?

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