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This Year In Medicine 2025

Opinion|Videos|April 11, 2025

Utilizing Patient Factors to Guide Treatment Selection in Atopic Dermatitis

Author(s)Linda Stein Gold, MD, Lisa Swanson, MD, PhD, James Song, MD

Experts discuss situations where an oral JAK inhibitor might be prescribed initially over a biologic for moderate to severe atopic dermatitis (AD), noting advantages such as oral administration, quicker onset of action, and convenience, which may make it a preferred option for some patients.

Episodes in this series

EP. 1 The Role of the JAK/STAT Signaling Pathway in Atopic Dermatitis

EP. 1 The Role of the JAK/STAT Signaling Pathway in Atopic Dermatitis

EP. 2 JAK1 Selective Inhibition and the Impact of Selectivity on Efficacy and Safety

EP. 2 JAK1 Selective Inhibition and the Impact of Selectivity on Efficacy and Safety

EP. 3 Long-Term Efficacy and Safety of JAK Inhibitors in Atopic Dermatitis

EP. 3 Long-Term Efficacy and Safety of JAK Inhibitors in Atopic Dermatitis

EP. 4 Understanding the Origins of the Boxed Warning for JAK Inhibitors

EP. 4 Understanding the Origins of the Boxed Warning for JAK Inhibitors

EP. 5 Communicating With Patients on the Safety of JAK Inhibitors in Atopic Dermatitis

EP. 5 Communicating With Patients on the Safety of JAK Inhibitors in Atopic Dermatitis

EP. 6 Laboratory Monitoring Plans for Oral JAK Inhibitors

EP. 6 Laboratory Monitoring Plans for Oral JAK Inhibitors

EP. 7 Oral JAK Inhibitors’ Place in Atopic Dermatitis Guidelines

EP. 7 Oral JAK Inhibitors’ Place in Atopic Dermatitis Guidelines

EP. 8 Utilizing Patient Factors to Guide Treatment Selection in Atopic Dermatitis

EP. 8 Utilizing Patient Factors to Guide Treatment Selection in Atopic Dermatitis

EP. 9 Addressing Treatment Response and Switching Among Systemic Therapies in Atopic Dermatitis

EP. 9 Addressing Treatment Response and Switching Among Systemic Therapies in Atopic Dermatitis

EP. 10 Oral JAK Inhibitor Dose Escalation in Atopic Dermatitis Treatment

EP. 10 Oral JAK Inhibitor Dose Escalation in Atopic Dermatitis Treatment

EP. 11 Key Takeaways on the Role of Oral JAK Inhibitors in Atopic Dermatitis Management

EP. 11 Key Takeaways on the Role of Oral JAK Inhibitors in Atopic Dermatitis Management

Video content above is prompted by the following:

What are some circumstances where you would prescribe an oral JAK inhibitor for moderate to severe AD initially over a biologic?
What advantages might a JAK inhibitor have over a biologic?

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