A recent meta-analysis of 31 randomized controlled trials with 4500 participants showed that metformin treatment significantly decreased weight, improved dyslipidemia and insulin resistance, and reduced the incidence of new-onset diabetes by 40%, with beneficial effects maintained over time. Further studies will show whether the metabolic improvements achieved with metformin treatment will ultimately result in a decrease in cardiovascular morbidity and mortality.
Cardiovascular disease accounts for 65 percent of patient deaths among people with type 2 diabetes.
Hemodialysis has evolved over the last 50 years as a life-saving treatment for people with renal failure. Now, there is a new treatment.
What has changed in diabetes medicine over the years? In this ongoing series exploring "Old Tyme Medicine," Bradley Schmidt takes a look at treating diabetes -- then, now, tomorrow, and beyond.
Insulin inhibits a gene regulator protein known as FOXO, important in diabetes metabolism, tumor suppression and stem cell maintenance. Studies are now showing reduced insulin leads to greater stress resistance and longer life.
