Type 2 Diabetes

Although some studies have hinted at a possible role for metformin in pain management, a recent investigation found no difference in pain scores among diabetic patients who used metformin and those who did not

Researchers study whether or not GLP-1 affects pancreatic amylase or lipase plasma concentrations.

The Paleolithic (grain-free) diet is gathering steam among dieters and health conscious individuals alike. Proponents consume only items that, hypothetically, cavemen would have had access to. They claim that modern man can't metabolize comparatively new types of food, and our reliance on processed foods has increased rates of obesity, heart disease, and diabetes.

Test your knowledge of recent findings in SGLT2 inhibitor efficacy and safety research.

It can be difficult to determine which combinations of antihyperglycemic medications might work best, and for which patients. A recent review investigates combined therapy, with a focus on the newer DPP-4 and SGLT2 inhibitors.

We highlight 3 recent studies concerning pregnancy and diabetes and ways to potentially reduce health risks of both mother and child.

Diabetic kidney disease does not have the telltale signs of other conditions which can make it difficult to spot. However, with the right tests patients can get the treatments they need.

One of the newest developments in the treatment of diabetes is the GLP-1 receptor agonist. With different forms intended for different populations it continues a longstanding pattern of bringing new medications into the pool of options for doctors to choose from.

A recent study looked at whether metabolic syndrome confers a greater cancer risk than the sum of its individual components and component associations, and whether it is a useful predictor for future cancer risk.

Obesity contributes to significant morbidity and mortality among primary care patients. This paper summarizes options for pharmacological management of obesity. Medications approved for obesity are Phenteremine/Topiramate, Orlistat, Lorcaserin, Naltrexone/Bupropion, Liraglutide.

As the diabetes epidemic continues to grow doctors are being faced with the task of stopping or reversing the trend.

Study results show that the combination of metformin and glibenclamide is as effective as insulin in achieving glycemic control in women with gestational diabetes and may be a more acceptable and cost effective therapy.

Empagliflozin, a diabetes drug that controls glucose levels, may also help ameliorate erectile dysfunction in patients with type 2 diabetes mellitus.

With certain strains already proving to be resistant to treatment with antibiotics, Staphylococcus aureus is posing another major health threat.

People who have type 2 diabetes —but not type 1— are statistically less likely to get amyotrophic lateral sclerosis (ALS), a new study found.

With the global boom in type 2 diabetes mellitus, many patients have greatest access to and are well-cared for by their primary care practitioners (PCPs). For those with basic, predictable, garden-variety diabetes, PCPs are perfectly capable of helping them. It's unclear when referral to a specialist for consultation or chronic management is most sensible.

Obesity rates have climbed nearly 50 percent since 1997, with as much as 30 percent of the population classified as obese. There is strong belief within the health care industry that obesity should be treated as a primary medical condition, with physicians playing a major role. Evidence suggests that patients are more likely to lose weight when they are advised by their primary care physicians to do so.

GLP-1 receptor antagonists have been associated with thyroid cancer in rodents, and in fact carry a boxed warning about the potential for cancer in humans. This leads many clinicians to ask if they should be concerned about using these drugs in patients who have or develop specific types of thyroid cancer

Sitagliptin appears to have beneficial systemic and adipose anti-inflammatory effects in combination antiretroviral therapy-treated HIV-positive adults with impaired glucose tolerance. The drug may prevent cardiovascular problems by reducing inflammation linked to heart disease and stroke in this patient population.

The results of the largest study of its kind to date indicate that new antipsychotic medications-including quetiapine, olanzapine, and risperidone-do not appear to put women at additional risk of developing gestational diabetes, hypertensive disorders, or major blood clots that obstruct circulation, all conditions that often develop during pregnancy or with the use of older antipsychotic medications.

More than 13,000 physicians and cardiovascular team members attended the ACC 2015 meeting in San Diego on March 14-16, 2015. In this issue of Cardiology Review, we focus on 6 important studies presented at ACC 2015: LEGACY, OSLER, PEGASUS, EMBRACE-STEMI, MATRIX, and CoreValve.

Mortality in patients with type 1 diabetes mellitus (T1DM) is higher than in the general population, and whether mortality improves or alters with glycemic control is unknown.

Our endo blogger has her theories about why doing what you thought you loved just seems to sap your soul.

China's type 2 diabetes mellitus (T2DM) epidemic continues to be a pervasive, costly health care issue, with proportions surpassed only by epidemic here in the US. The majority of T2DM treatment guidelines recommend metformin as the first-line anti-hyperglycemic agent for diabetes management due to its relative safety, tolerability, and cost-effectiveness.

Albumin -- the most abundant protein in the human body -- has many roles. It transports hormones, fatty acids, and other compounds. It buffers serum pH, and maintains osmotic pressure. Now, it appears that albumin may be a tool that could be used in diabetes management.