American Society of Hematology

Early initiation reduces hospital stays and length of IV opioid use.

Analyses of vital sign changes from the 6-minute walk test may be indicative of cardiopulmonary function and potential survival among patients with sickle cell disease.

The new findings show worsened outcomes among particular comorbid patient groups, as well as minority patients.

A discussion on what the future of monitoring the rare disease may entail, and how COVID-19 interrupted in-person assessment earlier this year.

The combination therapy was linked to a record phase 3 progression-free survival rate among a subpopulation of patients with the rare cancer.

A discussion with a study author and longtime expert on improving monitoring of the rare disease.

The furthest-progressed gene-edited therapy for a genetic disease reported historic efficacy data in ongoing phase 1/2 trials.

The app improved pain, fatigue, and quality of life in children with the disease.

A study finds that children with cognitive or emotional deficits trended towards an increased healthcare utilization.

Patients with baseline PROMIS-57 scores worse than population norms reported clinically significant improvements in 6 of 8 domains at 12 months post-treatment.

Faster initiation of COVID-19 treatment is associated with better outcomes in patients with hematological malignancies.

Patients with acute myeloid leukemia or myelodysplastic syndromes are at especially increased risk for increased disease severity and death.

New data from an ongoing trial showed patients achieved MRD negative status after a vaccine regimen—and have maintained status over a year.

Investigators evaluated patients from 3 Chicago hospital systems and assessed risk factors associated with thrombosis.

Early assessment from an Australian team of investigators is targeting a pathway linked to hemoglobin expression.

High levels of fetal hemoglobin have previously been linked to the mitigation of morbidity and mortality of sickle cell anemia.

Those without prior exposure to venetoclax experienced the most benefit.

In a 3-patient study presented at ASH, investigators believe they have found a therapeutic target to cure sickle cell disease.

In a study presented at the annual ASH meeting, investigators link biomarkers of cardiopulmonary, renal, and liver dysfunction with specific outcomes for adult sickle cell disease patients.

Results of a recent study from ASH 2019 is suggesting a combination of navitoclax and ruxolitinib could improve outcomes for patients with myelofibrosis.

Carfilzomib, dexamethasone, and daratumumab can be a good regimen for relapsed or refractory multiple myeloma, investigators found.

Results of a phase 3 study presented during the late-breaking sessions at ASH 2019 has found CC-486 provided patients with significant and meaningful improvements in overall survival (OS) and relapse-free survival.

The investigative monoclonal antibody may become the first therapy indicated for the rare autoimmune disease.

Results of a phase 3 study presented at ASH 2019 are suggesting blinatumomab was more effective than chemotherapy as a post-reinduction therapy in high and intermediate risk first relapse of b-acute lymphoblastic leukemia.

During the annual ASH meeting, investigators present phase 1 data from a new dose-climbing trial.

More patients with multiple myeloma could benefit from autologous hematopoietic cell transplantation, investigators found.

Results of the phase 2 MANIFEST study presented at ASH 2019 suggest CPI-0610 could be an effective treatment for patients with refractory or intolerant advanced myelofibrosis.

An analysis of nearly 7000 health records led to insights into factors of fragmented care for patients with sickle cell disease.

Results of an interim analysis of a phase 2 trial are suggesting enasidenib plus azacitidine may be more effective than azacitidine monotherapy alone.

New findings from a randomized, hospital-based trial in Nigeria show similar phase 2 results reported in the US for arginine as an adjuvant for vaso-occlusive pain episodes.