
Results from Alder Biopharmaceutical’s phase 3 study demonstrated reductions in migraine following quarterly infusions of both 100 mg and 300 mg eptinezumab versus placebo in patients with episodic migraines.

Results from Alder Biopharmaceutical’s phase 3 study demonstrated reductions in migraine following quarterly infusions of both 100 mg and 300 mg eptinezumab versus placebo in patients with episodic migraines.

Lead author Alexander D. Rae-Grant, MD, explains the measures taken to ensure the panel got their 16-year multiple sclerosis recommendations update right.

Researchers found that 100U of incobotulinumtoxinA significantly reduced unstimulated salivary flow rate during the 16-week trial and through the 48-week extension.

Already tasked with a burdensome regimen of therapy for nerve damage, some patients may just be looking for simpler relief.

The American Academy of Neurology has issued 30 recommendations for clinicians regarding disease-modifying therapies for multiple sclerosis.

The investigative therapy for SMA reported various efficacy results in a phase 3 extension trial.

Among patients with MS who began ocrelizumab treatment in the open-label extension, MRI lesion activity was almost completely suppressed.

A new study finding that 50% of low income Latino patients with MS suffer from depression is coupled with recent reports on their exclusion from clinical research.

How a litany of treatment options could be just a single breakthrough drug away.

How the brain processes thought and action can be heavily influenced by the size of the network it's exposed to.

Trial results on the recently FDA-approved gammaCore device will be presented at the American Academy of Neurology (AAN) annual meeting.

The investigatory therapy for secondary progressive MS returned even more promising post hoc analysis prior to its FDA consideration.

A wrist-worn neuromodulation device delivers a nerve stimulation pattern tailored to the patient’s tremor.

The investigational therapy is first being researched for safety and dosage rates before efficacy is considered.

Study results show 30.3% of difficult to treat patients taking erenumab saw at least a 50% reduction in monthly migraine days.

Sephy Philip, PharmD, discussed the results of the ANCHOR trial, as well as the subgroup analysis.

Steve Deitelzweig, MD, discussed the real-world usage of direct-acting anticoagulants in comparison with the conventional warfarin, as well as the benefits they have shown based on a large data analysis.

Hadley Wilson, MD, spoke about the new heart failure guidelines and how the ACC is attempting to make them more technologically available, as well as the ACC's efforts to connect with cardiologists on a more worldwide scale to help improve cardiac outcomes globally.

A novel subretinal implantation of a stem cell-based bioengineered patch may restore vision or prevent further vision loss.

Justin Davies, MBBS, MRCP, PhD, discussed the cost-effectiveness analysis of the DEFINE-FLAIR trial comparing iFR and FFR for patients requiring PCI.

Incorporating underused, but available, imaging technologies like PET/CT to test for calcium in coronary arteries more precisely predicts those at risk for MI and similar threats.

While copayment reduction significantly affected clinician’s choice of medication and improved patient persistence with treatment, it did not impact clinical outcomes at 1 year.

Larry Allen, MD, was part of a deeper look into the hospital readmissions reduction program (HRRP), and what the data that have been presented about it actually mean.

For patients with heart failure, the influenza vaccine can result in a mortality reduction up to 50% in season and 20% out of season.

Listening to music may help prolong exercise and participation, and may possibly have broader implications for exercise.

Findings suggest climate change may increase MI risk.

The risk of myocardial infarction was 2.4-fold higher in patients on short-term P2Y12 inhibitors after 18 months and 5.1-fold higher from month 6 to month 18.

Andexanet was shown to reduce FXa inhibition activity by 91% for patients on apixaban, 88% for patients on rivaroxaban, and 75% for patients on enoxaparin.

No events of primary endpoint occurred in PFO closure arm, whereas it developed in 6 of 60 patients receiving medication therapy alone.

Aggressive supplementation with vitamin D3 just before and after surgery can completely eliminate the observed drop.