
A set of highlights from some of the more impactful research and data covered this past week in the dermatology field, covering breakthroughs in research and advanced treatment options.

A set of highlights from some of the more impactful research and data covered this past week in the dermatology field, covering breakthroughs in research and advanced treatment options.

The daytime-nighttime appliance named DNA, serves as a novel alternative to existing treatment options for mild-to-moderate obstructive sleep apnea.

Patients with AF experienced worse 90-day outcomes than those without AF, even with comparable, successful reperfusion outcomes.

Results indicated similar outcomes between those who underwent tonsillectomy and mUPPP, with minor differences favoring the tonsillectomy group.

Children definite motor problems were more likely to have psychotic experiences compared to children with no definite motor problems.

Data from a 2019 survey of more than 5000 cardiologists across the globe suggests 28% of the field may be experiencing some form of mental health condition, with results also shedding light on predictors of mental health conditions.

New research identified gene-corrected autologous keratinocyte grafts as useful for treating recessive DEB patients.

The prevalence of HBV among people who inject drugs was highest in East and Southeast Asia and lowest in Western Europe.

Using data from more than 55,000 people with diabetes using metformin is providing new insight into the apparent reductions in risk of negative cardiovascular and renal outcomes as well as all-cause mortality with use of SGLT2 inhibitors.

The phase 3 GOBI study endpoints was significantly greater with NOV03 versus hypotonic saline on the change from baseline at Week 8.

The FDA requested additional data showing the levels of a nitrosam impurity was below the set threshold throughout the life of vonoprazan.

The retrospective study reported the presence of ADAs was associated with lower drug levels, and higher ADA levels were associated with increased risk of TNFi therapy failure.

Using data from more than 25,000 preschool-aged children in Sweden provides an overview in trends of weight gain and BMI changes that may have impacted pediatric populations during the COVID-19 pandemic.

New research into students’ understanding of the dermatology field suggests greater knowledge and exposure may instill greater appreciation for it among medical students.

Ulcerative colitis was considered an independent risk factor, while Crohn’s disease and unclassified inflammatory bowel disease were not.

Using real-world data from the US, Japan, and Sweden provides insight into contemporary trends in GDMT use, including initiation, uptitration, and discontinuation, following hospitalization among patients with heart failure with reduced ejection fraction.

New data suggests occupational exposure to certain melanocytotoxic chemicals may lead to vitiligo.

Patients with late-onset depression died on average 1 year earlier than those with early-onset depression or those without late-life depression.

The lowest mean utility value was observed in the most severe disease state of constant diplopia and large proptosis.

In a summary of a symposium from the 2021 EADV Congress, the writers describe patients’ difficulties in living with psoriasis and adhering to treatments.

Michael J. Ackerman, MD, PhD, discusses the simplicity and availability of education around CPR and defibrillator use, and the role of clinicians in raising public health preparedness.

Promising results from the IMerge phase 3 clinical trial met the primary and secondary endpoints in the investigation of imetelstat, a novel telomerase inhibitor developed for hematologic malignancies.

A post-hoc analysis suggests that increased dietary nitrate intake was associated with a decreased risk of late AMD, but this association was attenuated after the addition of plant-based dietary patterns.

The topline phase 2b data shows both 75 mg and 150 mg doses of atacicept resulted in a 31% mean reduction in proteinuria.

A Mayo Clinic cardiologist discusses the national variability in CPR and AED access, and the actions that saved Hamlin's life during Monday Night Football.

Exploratory analyses of data from the Look AHEAD trial suggest maintaining an HbA1c level of 7% or less was associated with smaller increases in frailty index over the 8-year study period when compared to their counterparts with an HbA1c level of 8% or greater.

Parenting stress, negative parenting practices, broken parental partnership, critical life events, parental psychopathologies, socioeconomic status, and single-parent family were all significantly associated with ADHD symptom severity.

A recent study examined the increased rates of eczema on the hands of health workers more during the COVID-19 outbreak.

The data from the DPPOS cohort report no difference in AMD presence or severity between metformin, intensive lifestyle intervention, and placebo arms.

Jesse Morse, MD, a sports medicine specialist, discusses commotio cordis and how to effectively communicate with athletes and parents of young athletes about the diagnosis in the wake of an incident where a player collapsed during a recent NFL game.