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Dr. David Hudesman expects drug developers to continue to target biologics for the treatment of IBD.

Repeated metabolite monitoring with subsequent dose optimization resulted in 67.2% of patients achieving therapeutic levels after 1 year and 87.8% of patients achieving steroid-free remission, while 90% had no therapy escalation or surgery.

Prior to the launch of FSR's webinar on pulmonary sarcoidosis, Mary McGowan, CEO, discusses the private listening session held with the FDA that addressed the critical needs in the field.

Dapagliflozin consistently reduced the risk of CV death or HHF, HHF alone, and progression of kidney disease regardless of background use of CV medications, investigators say.

Patients treated with LAIAs had a lower risk of hospitalization for any cause, hospitalizations for psychiatric disorders, hospitalizations for schizophrenia, and incident suicide attempts compared to patients treated with oral antipsychotics.

Cross-sectional data suggest a discontinuity in endothelial cell–density measurements just below 2500 cells.

The age-adjusted mortality rates for heart failure in young adults increased from 2.36 in 1999 to 3.16 in 2019.

Symptom flare-ups in patients on a gluten-free diet were significantly lower than in patients on a high-gluten diet.

The prevalence of suicidal was 10.9% in studies that included child-reported outcomes for child only and 10.4% for child and parent combined.

Dr. Kushner discusses obesity as a risk factor for CVD and how preventive cardiologists can better target weight management to support patient health.

The indication to Arcutis makes the once-daily topical cream the first marketed PDE4 inhibitor of its kind.

The highest adjusted probability of CGM use occurred in middle adulthood, while the probability of CGM utilization decreased with increasing age in older adulthood.

After March 2020, overdose deaths not involving methadone continued to increase whereas methadone-involved overdose deaths remained stable.

The association with depressive symptoms was greater when race, ancestry, or national origins among Hispanic or Latino participants was the main reason for discrimination.

An analysis of survey responses show tolerance toward public health official harassment and threatening has worsened since 2020.

For the July 2022 episode of Diabetes Dialogue: Therapeutics, Technology, and Real-World Perspectives, hosts Diana Isaacs, PharmD, and Natalie Bellini, DNP, sit down to provide perspective on the latest advances in the fight to cure type 1 diabetes and offer insight into their experiences at the Practical Ways to Achieve Targets in Diabetes Care Conference held in Keystone, CO in mid-July.

The 10-year cumulative incidences for HCC and mortality were significantly higher in the HBV cohort with heavy alcoholism than it was for either HBV alone or alcoholism alone.

Investigators articulated the development and validation of an enzyme-linked immunoassay against hepatitis C virus (HCV). They suggest the implementation of this low cost assay among at-risk populations.

The increase does not appear to have a negative impact on post transplant survival, investigators say.

There are several early phase trials underway for new hepatitis B virus treatments.

The goal for many is to eradicate HCV by the year 2030.

There’s still much to be understood about gene therapy and its application to rare diseases like sickle cell, but at the progressive pace it’s moving at, gene therapy is likely to be integrated further into standard practice.

The patients prescribed stimulants were more likely to not have coexisting conditions than those treated with A2A.

A cohort analysis of Rhode Island data showed populations at high risk of SARS-CoV-2 exposure are at greater likelihood of reinfection, and would benefit even more greatly from vaccination.

Patients with autism had a fivefold increase in adjusted relative risk of self-harm.

New sensitizations to 2 or more allergens between baseline and 12 months were significantly lower in the sublingual group, compared to the control group.

There was a direct association between consuming honey, ham, seafood, organ meats, salt, fruits on trees, fruit juice, olive, and nuts and the probability of developing IBD and ulcerative colitis.

The investigators found the overall age-standardized prevalence of depression based on the CIDI-SF scale was 5.7%, significantly higher than the self-reported rate of 0.5%.