News

Adults 40 years and younger generally aren't tested for lipid level risk—a byproduct of national guidance and clinical trial needs.

Patients with type 2 diabetes treated with triple therapy had less hepatic steatosis and fibrosis and significantly improved insulin sensitivity versus conventional therapy.

The team estimated the time to individual plasma glucose recovery following exposure to the medication.

Data show the age-adjusted prevalence of hyperinsulinemia in adults without diabetes increased by 18% in the study population between 1999 - 2000 and 2017 - 2018.

In keeping with earlier data, investigators suggested that metabolic syndrome was associated with severe cases of infection.

Data show the HR of the risk between T2D and T2D rates of developing complications were 1.88 (95% CI, 1.13 - 3.12; P = .02) for any diabetic retinopathy.

Nearly half of patients not in clinical remission achieved de novo clinical remission after 1 year in the maintenance study.

Authors suggest children with uncontrolled asthma should be considered for priority for COVID-19 vaccination.

Investigators recorded “remarkable variation” in CLRD hospitalization and mortality rates in 62 counties in New York state.

Nearly 70% of all vitiligo patients included in the study remained pigmented after systemic immunomodulatory treatment, with no evidence of recurrence of the disease.

The approval of daratumumab and hyaluronidase-fihj plus carfilzomib and dexamethasone is for treatment of adult patients with relapsed or refractory multiple myeloma who have received 1 to 3 prior lines of therapy.

Copy number variations were broadly associated with an increased risk of autism spectrum disorder and ADHD.

Significant 2-way interactions were found of atopic dermatitis with sleep disturbance as predictors of ≥75th percentile for poor task completion at 9 years of age.

The recombinant vaccine resulted in higher rates of seroprotection in all subjects, particularly those 45 years and older.

Recurrent VTE shows a higher rate than expected for patients with subsegmental pulmonary embolism without proximal deep vein thrombosis managed without anticoagulation.

IBD patients also were more likely to have bloody diarrhea and abdominal pain.

Endoscopies can be costly, invasive, and time-consuming as a way to assess disease active and infliximab efficacy in IBD.

A NDM cohort in Israel found those with TNDM were taller and heavier compared to PNDM, while chronic diabetes complications developed in patients with long-standing NDM.

The ergonomic device for the treatment of diabetes is the only insulin patch pump for closed loop integration able to be used with standard, pre-filled pump cartridges.

Recent studies have indicated more community spread of C difficile infections.

VX-880 stem cell-derived therapy demonstrated restoration of insulin production and was generally well-tolerated in T1D treatment.

Data show the multivariable-adjusted HR for increase in seafood consumption of 1 oz per day and all-cause mortality was 0.84 and for CVD-related mortality was 0.89.

More global studies on the prevalence of celiac disease are needed outside of the US and Europe.

Dr. Mulshine details the how low-dose CT scanning can result in “exquisite resolution” of structures in the lung in patients with lung cancer and smoking-related diseases.

Patients with history of VTE, peak D-dimer ≥3 μg/mL, and predischarge CRP ≥10 mg/dL were at high risk of experiencing new onset of VTE after hospital discharge.

Despite some overlapping risk factors, investigators noted that no common risk factors were identified in all 3 conditions.

Investigators added that this risk might possibly be through intrauterine effects, while associations with wheezing might be confounded by familial clustering factors.