Cardiology

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Albumin -- the most abundant protein in the human body -- has many roles. It transports hormones, fatty acids, and other compounds. It buffers serum pH, and maintains osmotic pressure. Now, it appears that albumin may be a tool that could be used in diabetes management.

A 28-year old man comes in who recently arrived in southern California from South America and suddenly developed a "cold." His symptoms included productive cough, shortness of breath, chest pain, fever, weakness and malaise. He also reported unexplained weight loss. Sputum and blood specimens were obtained for acid-fast smear examination and culture. A single posterior-anterior chest radiograph was obtained as part of his initial evaluation.

The American Heart Association was one of the first organizations to advocate dietary changes to decrease the risk of coronary heart disease (CHD). The organization's first recommendation appeared in 1957 advising a decrease in the amount of fat intake to decrease atherosclerosis risk. Today, a different approach is recommended, which considers the diet as a whole, with recommendations of what to both include and avoid. Among other nutritional and lifestyle recommendations, the AHA advises the consumption of 2 servings of fish weekly for both men and women.

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It is well established that among patients with the clinical syndrome of heart failure, approximately half have preserved systolic function, known commonly as heart failure with preserved ejection fraction (HFpEF). Although originally considered to be a syndrome that pathophysiologically involves diastolic dysfunction, ongoing investigation suggests that although diastolic abnormalities may be present in many patients, other aspects of pathophysiology likely also contribute to symptoms. This study examined the association of beta-blockers with mortality in patients with HFpEF.

It is widely accepted that sexual activity is an important component of quality of life for men and women with cardiovascular disease (CVD), as well as for their partners, and is a safe activity, in general. Yet, older studies show that most CVD patients do not believe they have been educated by health care providers on when to resume sexual activity or any necessary restrictions following acute myocardial infarction.

Physicians may think patients over 80 are too old to benefit from agressive care to treat unstable angina or clogged arteries that caused a heart attack. Think again, a Norwegian researcher said at the American College of Cardiology meeting in San Diego, CA. These patients were 47% more likely to survive and healthier after invasive procedures than a group that got non-invasive care.

Having worked at Cedars Sinai since 1982 Robert J. Siegel, MD, has seen a lot of changes in the medical profession and helped many doctors hone their craft as they begin their own work in the field.

Sunil Agarwal, MD, from Mount Sinai Hospital in New York, discussed the results of his research on the use of continuous cardiac monitoring to monitor elderly patients for atrial fibrillation and sub-clinical arrhythmia and help reduce their risk of stroke and other health complications.

AstraZeneca researchers report that a new drug call MED12452 is being developed as an antidote for patients who need to reverse the effects of ticagrelor (Brilinta/AstraZeneca) on an emergency basis. That could be important for patients taking ticagrelor who need emergency surgery or are bleeding from an accident.

A 73 year-old man presents to the emergency department from his internist's office where he had complained of palpitations and light-headedness that began 4 hours earlier after his daily exercise regimen. He did not appear distressed, but his heart rate was 160 beats per minute. Blood pressure was 140/90. He had no light-headedness at the time, but continued to report palpitations. An ECG was performed.