Endocrinology

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Whether direct-to-consumer advertising is a good or bad thing remains a matter for debate, but what is not up for discussion is the need for due diligence on the part of physicians in managing patients who are motivated by those ads to seek medical attention.

Meta-analysis of clinical trial data on the use of antidepressants and anticonvulsants for the treatment of painful diabetic neuropathy indicates gabapentin is the most efficacious agent for this condition, while the side effects associated with amitriptyline make it the least tolerable treatment option evaluated in the study.