Gastroenterology

Company is seeking FDA approval for its all-oral, interferon-free regimen for the treatment of adult patients with chronic genotype 1 hepatitis C.

New guidance from the WHO includes nine key recommendations covering screening, treatment, alcohol use assessment and counseling, and measures to prevent transmission of the virus.

SAPPHIRE II trial results show sustained virologic response in 96% of treatment-experienced patients with genotype 1 hepatitis C who were treated with interferon-free, triple-drug regimen.

Fitful nights of sleeplessness and daytime fatigue were more common among people with hepatitis C regardless of whether they had cirrhosis of the liver when compared to the healthy control group involved in a small study.

Postoperative surgical site infection is exceedingly rare after hemorrhoidectomy, and routine antibiotic prophylaxis seems to be unnecessary.

Genetics, diet, past trauma, and anxiety have all been thought to play a role in the cause of irritable bowel syndrome, but new research has found a clue to the disease.

Sodium picosulfate, a commonly prescribed medication for bowel prep prior to colonoscopy, is associated with increased risk of hyponatremia in older adults compared to polyethylene glycol.

Patients with unreasonable or uninformed expectations are often unprepared for the postoperative period and dissatisfied with their outcomes. As a result, healthcare professionals are dedicating more time to studying and managing patient expectations, including making sure all involved have a clear understanding of what to expect in terms of risks and benefits.

Many adhesions are asymptomatic, but in some patients, they can cause pain, small bowel obstruction and other postoperative issues, as well as increase cost and complicate surgical suite workload.

Although molecularly targeted cancer therapies are generally safe and more effective than previous treatment options, some serious adverse events can occur.

Aggressive medical therapy might be more closely linked to mortality and malignancy in pediatric inflammatory bowel disease than the condition itself, according to a new study.

A minimally-invasive, surgically-implanted esophagus band developed at Stony Brook University Hospital effectively reduces symptoms of gastroesophageal reflux disease (GERD).

While there are no medical safety reasons to avoid becoming pregnant after a tummy tuck, there is no definitive way to ensure the results of the procedure will remain intact throughout a new pregnancy.

In 10 randomized controlled studies, patients who chewed gum after elective colorectal surgery had shorter lengths of hospital stay and were less likely to experience complications.

Patients who have experienced hemorrhage and sepsis seem to gain the most benefit from damage control procedures if the surgeon uses careful patient selection.

In his presentation, George Therapondos, MD, a hepatologist at the Ochsner Medical Center, detailed how to manage inpatients with cirrhosis that progresses to liver failure and gastrointestinal bleeding.

Primary prevention measures for upper GI bleeding should include NSAIDs, antiplatelet therapy, and anticoagulants appropriately, while secondary preventive measures should include testing and treating H. pylori and using long-term PPIs when appropriate.

Although 3-year survival and cancer recurrence rates are comparable for patients who have laparoscopic or open surgery at any stage of colon cancer, older patients who undergo a laparoscopic procedure have a significantly less likelihood of being admitted to a nursing home compared to those who have open surgical resection.

Case study presented at CHEST 2013 details the experience of a patient with hepatitis C who, after undergoing liver transplant, died after developing a serious lung infection and other complications.

With 10% of Americans contracting ulcers, pharmacists can be a valuable source of education for patients regarding the causes of peptic ulcer and the pros and cons of available treatments.

Study results show that SIRS on admission and at 72 hours after is associated with a higher incidence of pancreatic necrosis, an important risk factor contributing to death in patients with severe acute pancreatitis.

Two studies at the American College of Gastroenterology's 78th Annual Scientific Meeting analyzed the health outcomes of inflammatory bowel disease in the U.S. and Canada.

Steven P. Levine, MD, says the implications of altering the microbiome may extend beyond C. difficile to mental health, given the new insight into the connection between the gut and mind.

In a clinical review published in Clinical and Experimental Gastroenterology, researchers from Iwate Medical University in Japan evaluated the long-term safety and efficacy of the novel serotonin-receptor agonist ramosetron in patients suffering from diarrhea-predominant irritable bowel syndrome (IBS-D).

Even when it's administered in a low-dose form that resists gastric acid and prevents tablet dissolution in the stomach, aspirin therapy causes peptic ulcer and increases the risk of 30-day mortality resulting from gastrointestinal (GI) disorder progression.