Major Depressive Disorder

If approved, Spravato would become the first novel mechanism of action in 30 years to treat major depressive disorder.

The US Preventive Services Task Force has recommended that clinicians refer pregnant and postpartum persons who are at risk of depression for counseling services.

Trazodone is a depression drug, but it blocks the integrated stress response, so it may be a good candidate for ALS.

Physicians on the front lines of care should be empowered to consider alternative treatment options for patients in significant need.

A new cohort analysis shows patients switching or adding on the antipsychotic drug are not at a worse risk of suicide or other adverse events.

Hilary Baldwin, MD, debunks the myths behind the nodular acne therapy she claims is a miracle drug.

Why certain age-related factors particularly impact the mental health of women at the age their menopause symptoms appear.

The antipsyhoctic could receive a new indication in 2019, and though the field of bipolar disorder care is far from perfect, it should improve with this addition.

The study focused on patients with bipolar or depressive disorder.

A retrospective study showed which patients with substance use disorder may have less successful antiepileptic drug treatment.

Patients treated with SAGE-217 had significantly improved depression scores and were more likely to achieve remission than those receiving placebo.

Investigator Anita Clayton, MD, shares insights into the new vortioxetine data and its implications for patients with depression and treatment-emergent sexual dysfunction.

About half of all MS patients experience an episode of depression during their lifetimes, but most interventions are drug-related or psychiatric.

Most of the patients in the study were taking concomitant antidepressants and/or antipsychotics, and mood disorders remained stable during treatment with valbenazine.

Ezogabine was not marked as an antidepressant but seemed to be an effective treatment in a small study.

A meta-analysis of more than 7 million patients confirms that just 1 instance of a concussion or mild TBI is associated with a two-fold greater risk of suicide.

Long-term lung inflammation associated with allergen exposure is linked to the development of anxiety later in adulthood, according to a new study.

A supplemental new drug application (sNDA) for vortioxetine (TRINTELLIX), a prescription medication for the treatment of adults with major depressive disorder (MDD), has been accepted by the FDA.

Increased access to proper mental health care is a key weapon in the battle against the deadly opioid epidemic, according to a recent study.

People with depression exhibit an unexpected increase in volume on the left side of the hypothalamus, the brain region responsible for physical wellbeing.

Clinicians should encourage natural light exposure to reduce the risk of postpartum depression in women with third trimesters in the fall, study suggests.

Why delving into the symptoms of the most at-need patients is critical for care.

Instances of sexual harassment are associated with high blood pressure and poor sleep for women in midlife, while sexual assault is associated with poor mental health and sleep.

The robustness of neural responses to positive and negative events may modify adolescent girls’ risk of depression, according to a new study.

Some of the most impactful predictors of future asthma attacks include a history of prior attacks, depression, and vocal cord dysfunction, investigators found.