Pulmonology

An increased morbidity risk has been found to be associated with central sleep apnea in infants with congenital heart disease by University of Arizona investigators.

Continuous positive airway pressure was previously defined as the primary treatment of OSA, as well as related issues like mask fits. Weight management has been continuously unaddressed in guidelines and literature.

The study results may help enable the development of nasal microbial markers of asthma for detection and disease monitoring.

The patient population tends to have a more unbalanced immune profile to that of European American patients, indicating a potential for tailored treatment options to combat inflammation.

Stay up-to-date on the latest rare disease news by checking out our top 5 articles of the week.

Patients with asthma and eosinophilia have thicker airway nerves, according to new research.

The combination of montelukast and budesonide was found more effective than budesonide alone in children with chronic cough-variant asthma in a China retrospective study.

Many first responders were exposed to particulate matter that led to their development of World Trade Center Lung Injury, a collection of chronic respiratory conditions, such as asthma and emphysema.

Investigators found that asthma symptom severity results from the interaction of genetic susceptibility to pollution together with the severity of pollution exposure.

The company’s application for mepolizumab vied for it to serve as an add-on therapy to inhaled corticosteroid-based maintenance treatment in patients with COPD, as guided by patient blood eosinophil counts.

Deaths due to drug overdoses and suicides have contributed to decreasing US life expectancy, but other factors indicate that there is a deeper root cause driving these trends.

A new study of 4,000 Canadian women with asthma found patients who had higher body mass indices, smoked frequently, and had lower education faced higher risks of developing chronic obstructive pulmonary disease.

Study of abrupt versus gradual reduction of nicotine informs FDA-proposed rule on reducing cigarette nicotine to "minimally addictive" levels.

The treatment may be most appropriate for toddlers who are admitted to the hospital, have severe allergies, or are seen in the emergency department.

The results of a recent study revealed that the implementation of a comprehensive care plan for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) can be successful in reducing both readmission and mortality rates.

One Cleveland Clinic practitioner describes his real-world experience with the use of mepolizumab in patients with severe eosinophilic asthma.

New insights might help researchers improve the efficacy of LTA4H inhibitors.

A contributing mechanism responsible for the development of idiopathic pulmonary fibrosis has been identified.

A generic version of the 0.3 mg- and 0.15 mg-strength injectors has been approved for the treatment of patients that include those with life-threatening allergic reactions.

Experts argue that oral corticosteroids should be available at home for early use in asthma exacerbation.

The FDA has granted an orphan drug designation in a second indication to Martin Pharmaceuticals’ trimetazidine dihydrocholoride (LIVANTRA) for the treatment of pulmonary arterial hypertension (PAH).

Investigators find more evidence to support IgE as a reliable biomarker for targeted biologic therapy in asthma management.

The FDA has granted an orphan drug designation to Onspira Therapeutics’ OSP-101, the first and only inhaled interleukin-1 receptor antagonist (IL-1Ra) for the treatment of bronchiolitis obliterans.

In its phase 2 trial, acebilustat (CTX-4430) was found to show clinically meaningful improvement in pulmonary exacerbations in patients with cystic fibrosis.

New research outlines the role of neutrophil cytoplasts in severe asthma which could lead to new therapeutic pathways to treat the disease.