Ellipsoid Zone Integrity a Key Factor for VA in Eyes with nAMD Without Fluid
The best overall outcomes were attained in eyes without fluid and ellipsoid zone integrity preservation, investigators said.
Monotherapy Aflibercept Does Not Differ to Initial Bevacizumab for DME Care
An assessment of anti-VEGF dose regimen strategies concludes with little difference in outcomes among treatment arms at 2 years.
Pursuing Tailored Care for Diabetic Macular Edema
The retina field is equipped with ideal therapy and research informing implementation. Now it needs greater patient buy-in.
Intravitreal Injections Linked to Psychosocial Burden in Retina Disease Patients
Assessment from a patient survey showed an association between increased rates of injection treatment and increased restriction on usual activity for patients.
Factors Influencing Treatment of Diabetic Macular Edema
Rishi P. Singh, MD, discusses new VISTA/VIVID data showing what really influences a patients' likelihood and time to DME resolution when treated with aflibercept.
Long-Term nAMD Patient Buy-In Is Still Lacking for Anti-VEGF Therapy
Theodore Leng, MD, MS, defines the trends of patient discontinuation, and how direct caregivers may help to reduce risk of losing patients.
How Virtual Visits, Port Delivery System Therapy Can Benefit Retina Practices
Arshad Khanani, MD, MA, explains how new measures made available to ophthalmology will help address a quickly growing patient population.
Assuring Optimal Implant Insertion of Port Delivery Systems for Anti-VEGF
Veeral S. Sheth, MD, MBA, discusses what ophthalmologists will need to learn about PDS application for patients with AMD.
Anti-VEGF Continuation Wanes After 3-6 Years for Patients with nAMD
Theodore Leng, MD, MS, discusses new findings based on IRIS registry data showing long-term discontinuation trends in patients.
Arshad Khanani, MD, MA: Applying Ranibizumab PDS in Practice
An approval may be pending for the unique delivery system. An expert explains its benefit for nAMD patients and physicians alike.
Hybrid Ophthalmology Telemedicine Could Exist Beyond COVID-19
A retina care team highlighted positive patient feedback from their makeshift system; could it be a long-term solution?
COVID-19 Delays in Retina Care Are Driving Worse Vision Outcomes
A greater rate of intravitreal injection appointments were delayed last year, causing worse patient scores in BCVA and OTC.
COVID-19 Masking Did Not Influence Bacteria Eye Infections from Anti-VEGF Injections
New cohort analyses show endophthalmitis was not significantly reduced in treatment encounters where both physicians and patients were masked.
Varied Faricimab Dosing Regimens Non-Inferior to Aflibercept in Patients with DME
Findings from YOSEMITE and RHINE show a significant rate of patients on faricimab were able to extend their dosing to once every 16 weeks after a year of therapy.
Investigative Oral Retina Drug APX3330 Shows Favorable Safety, Tolerability
Positive phase 1 and 2 findings support an ongoing efficacy assessment of the Ref-1 inhibitor for diabetic retinopathy and diabetic macular edema.
Diabetic Macular Edema Trials Lack Accurate Patient Racial Representation
A new cross-sectional analysis from ASRS 2021 show White patients are generally overrepresented in randomized, controlled trials for DME.
Ranibizumab PDS, Faricimab, Gene Therapy and Top ASRS 2021 Headlines
Josh Mali, MD, of The Eyes Associates, joins HCPLive to review the key news and developments coming out of the American Society of Retina Specialists 2021 Scientific Meeting.
Patients Treated for Proliferative Diabetic Retinopathy Are Frequently Lost to Follow-Up
A cohort assessment of the IRIS registry database shows about 1 in 10 patients to receive anti-VEGF and/or panretinal photocoagulation discontinue therapy for at least 1 year.
Bevacizumab Step-Therapy Efficacious on nAMD Trial
There has been controversy over the efficacy and safety of step-therapy for neovascular age-related macular degeneration.
Ongoing Trial Assesses New Anti-VEGF Gene Therapy Injection for nAMD
No serious adverse events reported through 24 weeks of a 52 week trial.
Dexamethasone Implant and Anti-VEGF Therapy Effective for NAMD
Combining the dexamethasone implant with anti-VEGF treatment can restore foveal anatomy in eyes resistant to anti-VEGF injection.
Study Warrants Screening for Both Eyes in DME Patients
An interview with a Cleveland Clinic investigator on adjusting macular edema screening methods.
How Ophthalmology Has Evolved During COVID-19
A perspective on what's moved virtually, and what hasn't, since the pandemic began in March.
Early Combination Therapy Results Show Efficacy for Diabetic Macular Edema
In a phase 1b study presented virtually during ASRS 2020, investigators found a reduction in central subfield thickness after 12 weeks of OPT-302 combined with aflibercept injections.
Researchers Take an Overview Approach to nAMD Treatment Burden and Vision Analysis
The mean number of injections in the studies over 12 months was 9.36 ± 2.66, with a mean change in ETDRS letters was 7.86 ± 1.37.
Anti-VEGF Injections Associated with Cognitive Impairment in AMD Patients
Interim findings from a cross-sectional study shows a correlation between worse cognitive scoring and a greater rate of intravitreal injections.
Telescreening Programs Could Help Identify the Rates of Retinal Pathology
A total of 115 of 200 examined eyes had some form of diabetic retinopathy in data presented at the ASRS 2020 virtual meeting.
Strategies Needed to Improve Visual Acuity for Diabetic Macular Edema
Patients demonstrate visual gains from baseline but mean visual acuity worsens between 2 and 5 years.
Billing Codes Could be Useful in Capturing DME in Patients with NPDR
In research presented at ASRS 2020, investigators found 56% of patients with PDR had a DME code, with a sensitivity of 85%.