News

To the knowledge of researchers, this is the first demonstration to show C3a can stimulate basal deposit production by normal human RPE cells.

Researchers suggest a need exists for integration of hepatitis C treatment into all facets of addiction care for individuals who inject drugs.

Converting from brand-name levetiracetam to generic version does not greatly increase seizure frequency among patients with epilepsy.

Currently, FDA-approved fluoroquinolones include levofloxacin (Levaquin), ciprofloxacin (Cipro), ciprofloxacin extended-release tablets, moxifloxacin (Avelox), ofloxacin, gemifloxacin (Factive) and delafloxacin (Baxdela).

An isotopic-reinforced polyunsaturated fatty acids shows a reduction in cognitive deficits in a preclinical in vivo model of Huntington disease.

The issuance was in response to a request by the DoD, and after the FDA received a declaration from the Secretary of the Department of Health and Human Services.

Several promising new treatment developments are offering a ray of hope to Huntington’s patients, their at-risk children, and the clinicians who treat them.

The Center for Inquiry has filed a lawsuit against CVS for consumer fraud due to its sale and marketing of homeopathic medicines.

An online prevention program that uses a soap opera format was shown to be effective at lowering rates of STIs.

Researchers measured the VMAT2 inhibitors for clinical effectiveness, cost-effectiveness, and budget impact of these medications.

First-line protease inhibitors posed different risks for cardiovascular disease in an international study of adverse events in HIV patients.

At 48 months, intervention patients significantly fewer incidence rates for CIN3+ versus control patients, with a risk ratio of 0.42.

Data from the Alcyone MEMS Cannula (AMC), which can intratumorally administer the oncolytic adenovirus, may be an effective diffuse intrinsic pontine glioma (DIPG) treatment, according to recently presented data.

An analysis of pediatric ICU interactions found that physicians are far more likely to get a beneficial response from families when they show empathy to their emotions.

Previously, the benefit of exercise in mediating both CVD and depression was documented, but the association between midlife fitness with later depression and death from heart disease had not been.

Skyhawk Therapeutics and Celgene Corporation have entered into a 5-year partnership to discover, develop, and commercialize small molecule treatment options for patients with neurological diseases.

A modelling study showed that injectable PrEP could be more effective at reducing HIV transmission than oral PrEP.

CLR 131 was granted an orphan drug designation by the US Food and Drug Administration (FDA) for the treatment of Ewing’s sarcoma, a rare pediatric cancer.

The FDA agreed to remove a boxed warning from inhalant combinations of corticosteroid and long-acting beta-agonist following research from a collaboration of pharmaceutical manufacturers.

Utilizing research from the Age-Related Eye Disease Study 2, researchers found that MA and GA may be part of the same disease process affecting the visual acuity of patients with AMD.

An NYU study showed that physicians at small, independent primary care practices report much lower rates of burnout—13.5% compared to the 54.4% national average.

Stay up-to-date on the latest rare disease news by reading the top 5 articles of the week.

People of good conscience, including many physicians, are sharply divided on the ethics of MAID/PAS. Unfortunately, much of the support for this practice is founded on several myths and misconceptions regarding existing MAID laws and practices, according to Ronald Pies, MD.

Morie Gertz, MD, discusses a new treatment for hATTR amyloidosis patients, inotersen, as it makes its way towards FDA approval.

Researchers at Penn Medicine have found patients with more severe forms of neurodegenerative diseases possess more co-pathologies.

The anti-amyloid beta protofibril antibody resulted in slowed progression in ADCOMS, as well as a reduction of amyloid-PET measured amyloid accumulation in the brain.

Researchers found that patients with a documented penicillin allergy were at increased risk of developing MRSA (60%) and C. difficile (20%), in part due to alternative antibiotic use. However, when tested by an allergist, 95% were not actually allergic to penicillin.

New research suggests cirrhosis, not HCV status, is the reason diabetes rates are higher among HCV-infected patients.